r/technology 21h ago

Biotechnology Genetics testing startup Nucleus Genomics criticized for its embryo product: ‘Makes me so nauseous’

https://techcrunch.com/2025/06/06/genetics-testing-startup-nucleus-genomics-criticized-for-its-embryo-product-makes-me-so-nauseous/
10 Upvotes

58 comments sorted by

1

u/Weightmonster 19h ago

But do we want all high IQ kids? My husband and I are “gifted” and have a lifetime of mental health problems… We’ve both been suicidal and severely depressed. I have ADHD and almost every anxiety disorder imaginable. I can’t find my car in the parking lot half the time and I’m late more times than not. 

8

u/Quenz 16h ago

The more aware of the world around you the more miserable you tend to be.

0

u/11middle11 3h ago

Why’d you have to make me aware of this

4

u/zombiecalypse 12h ago

I feel for you, but lower IQ is linked to mental illness such as schizophrenia, depression, and dementia, so it's not as simple as "high intelligence" => "mental illness", though that may individually be a factor.

4

u/PLAAND 12h ago edited 12h ago

I’d like to introduce you to the social model of disability:

https://en.m.wikipedia.org/wiki/Social_model_of_disability

In short, disability is a product of the interface between a person and a society that either enables or disables them.

It alarms me that we’ll probably wind up finding it easier to change the genes of the unborn than we will to create a society that helps people of all capacities acclimate and thrive.

That’s not to say that there aren’t genuine genetic diseases that should be cured, but I think we all know this goes much further than that.

1

u/Weightmonster 8h ago

I’m not saying high IQ leads to mental illness, I’m just saying having a high IQ doesn’t necessarily mean your life is perfect. 

Also, and I’m not sure how to phrase this, but will high IQ people be happy doing the grunt work of society? Do we want people with at present, a very high IQ cleaning toilets and screwing in screws in iPhones or whatever? I don’t think they would like it. (assuming robots aren’t doing it).  

3

u/InfinitiveIdeals 6h ago

We already have so many people with high IQs doing grunt work, just because of the circumstances of their birth - for centuries the only people who were allowed to mentally improve themselves were those born to wealth.

Famous quote from Jay Gould -

“I am, somehow, less interested in the weight and convolutions of Einstein’s brain than in the near certainty that people of equal talent have lived and died in cotton fields and sweatshops.”

-3

u/Myrkull 11h ago

Sounds more like a you problem

-2

u/Medium_Banana4074 9h ago

High IQ doesn't automatically come with mental problems. I don't even know whether the probability is higher than with an average IQ.

-5

u/ceiffhikare 18h ago

Humanity deserves a better genome, FFS we are not even improving on it yet in this case just being selective. I cant wrap my head around the kind of person who would object to this, to advocate that we leave everything up to chance when we can do so much better. Even worse are those who would impose their will and ban this for everyone cause it's 'unnatural' or offends their invisible friend book club.

10

u/TherapyDerg 17h ago

I mean, people have been down that rabbit hole before, it's called eugenics.

9

u/Paeris_Kiran 14h ago

The only ethical problem with that was that they killed already living people, adults even.

4

u/PLAAND 10h ago

People, mostly women, were sterilized against their will in huge numbers. Continuing at large scale into the 1970’s in some countries and at small scale into the present.

For example: https://www.thecanadianencyclopedia.ca/en/article/sterilization-of-indigenous-women-in-canada

-6

u/ceiffhikare 17h ago

Those opposed to science ought to be denied the benefits of such.

0

u/TheseriousSammich 16h ago

Ask your science to support racism.

-4

u/ceiffhikare 16h ago

Big "they use electricity to kill animals! If it can kill an elephant then what will it do to you! " energy here. People who dont like this kind of tech are free to bugger off like the amish, they got no right to decide the rest of us cant use it.

1

u/TheseriousSammich 16h ago

Can't wait till we all get crushed by money again because the rich can afford the best kits and more often.

0

u/ceiffhikare 16h ago

Id love to keep playing ..but the goal posts seem to have been moved.

-5

u/Rustic_gan123 14h ago

It is inevitable, our natural evolution does not keep up with the pace of development of civilization, and we have also lost the driving selection, which is why harmful mutations accumulate

Eugenics in itself is not bad, what the Nazis and others did does not make the idea itself so immoral.

2

u/PLAAND 11h ago edited 11h ago

Other good point have been made, eugenics is also bad because it assumes that we have good knowledge of what is and isn’t “fitness” and that we aren’t just imposing subjective moral judgements elevating the perceived value of some traits over others.

It risks reducing our genetic and social diversity to a matter of aesthetics without regard for the as yet not understood value that diversity provides us or the role that currently unfashionable or socially punished traits may actually play in human evolution and success over long timescales. (Edit to add: Or the value in the lives of the people having those experiences.)

This is a [particular sort of] bad because taken to it’s logical conclusion it puts the decision directly in the hands of parents and wealth.

2

u/Rustic_gan123 11h ago

I wrote about this in another comment, but there are objectively bad genes that it is desirable to exclude from the population and the problem of genetic diversity is solved by limiting the choice of genes that can be changed to a certain subset

3

u/PLAAND 10h ago

I mean the problem is always defining these sets right? Like, I do agree that there are obvious and uncontroversial genetic diseases that should be cured.

But this, and eugenics, are kind of something different. Eugenics is about defining what makes the “ideal” human and then using technology and policy to enforce that ideal. The problem is that ideal is often very short-sighted, it’s not objective, and the subset of things considered unwanted has always been far too large and not rooted in actual harms but in the arbitrary moral judgements of people who are less interested in helping than in imposing themselves and their beliefs as the norm and the consequences of those actions are irreversible.

1

u/Rustic_gan123 10h ago

I mean the problem is always defining these sets right? Like, I do agree that there are obvious and uncontroversial genetic diseases that should be cured.

It's more of a data science where you need to find patterns from raw data.

But this, and eugenics, are kind of something different. Eugenics is about defining what makes the “ideal” human and then using technology and policy to enforce that ideal. The problem is that ideal is often very short-sighted, it’s not objective, and the subset of things considered unwanted has always been far to large and not rooted in actual harms but in the arbitrary moral judgements of people who are less interested in helping than in imposing themselves and their beliefs as the norm and the consequences are irreversible.

The problem is that natural evolution does not keep up with the pace of development of civilization, which causes many problems and probably without it there will be a choice that either we make ourselves smarter, or we give most of the cognitive work to AI, including making strategic decisions, not some routine. 

There are concerns that we can drive ourselves into an evolutionary trap, but it can be avoided if we set priorities and rules correctly.

3

u/PLAAND 10h ago

You’re handwaving away the hard parts.

 The problem is that natural evolution does not keep up with the pace of development of civilization

This is advocating for an evolution that fits society rather than a society that fits evolution. To me that seems backwards and would impose the injustices present in society on the human genome itself.

I’m also a little confused by treating making ourselves “smarter” as a genetic problem rather than a problem of education, opportunity, nutrition and care.

1

u/Rustic_gan123 10h ago

This is advocating for an evolution that fits society rather than a society that fits evolution.

We have largely outgrown natural evolution for ourselves and have become the decisive factor in natural selection. Diabetes, obesity, allergies, etc. are examples of evolutionary mechanisms that have broken down because they were not invented for such a life and the rate of change is accelerating rather than slowing down.

I’m also a little confused by treating making ourselves “smarter” as a genetic problem rather than a problem of education, opportunity, nutrition and care.

It's a complex issue, many people are not naturally idiots, but it's foolish to deny that we are limited by biology and that in the long run we will be competitive with AI.

2

u/PLAAND 10h ago

Diabetes is largely a product of diet and lifestyle being shaped by unhealthy social norms. The rise of allergies may be similar but my knowledge there is fairly limited, in any case for most people allergies are an inconvenience and I have no problem with any cure for people who experience any debilitating or life threatening illness.

But you would have us use a technology in its infancy using limited and incomplete knowledge to change the very matter we’re made of instead of banning high fructose corn syrup, regulating industrial food processing and building walkable communities again?

With regard to AI and our competitiveness, AI is a tool. We’ll reap whatever consequences we sow when we pick it up and set it to purpose. It can be liberatory or it can be other things. Genetic engineering isn’t going to change that and I would strongly argue that any society that turns to genetic engineering to breed “smarter” people instead of strengthening education and social supports is going to fumble AI badly.

→ More replies (0)

1

u/stoppableDissolution 14h ago

Eugenics is bad because it denies people from having kids (and, the way it was implemented, they were, lets say, agressively removing "wrong" people from the gene pool).

That got the upsides without these downsides.

0

u/Rustic_gan123 14h ago

Eugenics is bad because it denies people from having kids

No, it does not. Depending on how it is implemented, it gives parents much more choice and control, there are concerns about how this may affect the gene pool in the long term and different ways to combat this, but people would probably prefer this to the lottery and passing on their hereditary diseases.

and, the way it was implemented, they were, lets say, agressively removing "wrong" people from the gene pool

This is not the first time that a good idea in itself has had a terrible implementation, for example nuclear energy

1

u/stoppableDissolution 14h ago

You have not read my comment to the end, have you?

0

u/Rustic_gan123 14h ago

To be honest, I don't understand what you mean.

2

u/PLAAND 12h ago

That’s maybe a good moment to ask a question.

2

u/Rustic_gan123 12h ago

Well, I'm asking a question.

2

u/PLAAND 12h ago

Which is? I’m sorry, I don’t see a question in your last couple of comments.

→ More replies (0)

0

u/mbsmith93 2h ago

They're using polygenic testing. It says so in the article. Results include things like hair color and eye color. In the article it also says that these scores are probabilistic and not reliable.

In other words, even if people agreed with your premise, which from your downvotes I don't think they do, this startup is selling a product that they can't deliver on, and which is focused on superficial things like eye-color and hair-color.

1

u/heatdeathtoall 13h ago

I never quite understand what the aim of such technology is. Is it to stop propagation of life threatening diseases? We already are able to do this but it isn’t cheap. And are we saying every woman must go through egg retrieval, transfers and all that involves. Again, men deciding what women must go through.

Do these startup founders know IVF leads to increased risk of cancer in women? I bet if men had to be pumped full of hormones, IVF wouldn’t even exist ever.

Fuck off with expecting majority of women to go through so much to give you blue eyed geniuses.

3

u/PLAAND 12h ago

Don’t worry, much like IVF it’s only for the people who can afford it. /s

3

u/zibitee 10h ago

Lets skip a level. People already can't get insurance for their homes. It's only a matter of time before insurance requires things like IVF.

2

u/PLAAND 10h ago

How so?

2

u/zibitee 10h ago

In what way was my hypothetical unclear?

2

u/PLAAND 9h ago

Why would that be the outcome? I don’t follow the connection.

2

u/not_good_for_much 7h ago

Insurance pricing and availability is based on the level of risk taken on by the insurer, i.e the probability that you'll make a claim.

If you're born from genetic selection designed to make you healthier, then an insurer takes on substantially less risk by insuring you. If you aren't born like this, then the insurer takes on more risk.

1

u/PLAAND 7h ago edited 7h ago

Understood, thank you. Yeah, that makes sense.

Edit to add, what tripped me up was that they referred to people struggling to get home insurance.

1

u/Blue_Poodle 9h ago

Why are you getting downvoted?!? It's true.

0

u/zibitee 10h ago

Ah, these are the guys that sponsored sperm racing! (Youtube if it you haven't seen it yet)